Research
Research in this area is advancing rapidly and applications are proliferating, especially in the life/health sciences and biotechnology, chemical sensing, cosmetics, oil extraction, food industry, air purification, to cite a few. The bio-applications are broad and encompass a diverse range of areas that include micro total analysis systems (MicroTAS), lab-on-a-chip (LOC) technology, point-of-care (POC) clinical diagnostics, organ-on-chip, drug discovery and delivery and on-chip sensors. Boosted by the recent exhilarating developments in the design and utilization of microfluidic devices for fluid transport, the technology of the micro Total Analysis Systems (μ-TAS) has revolutionized the processes associated with sample handling, detection, and analysis in stand-alone integrated microfluidic platforms for bioassays. In order to design and optimize microfluidics-based devices for the above-mentioned applications, it becomes essential to understand the underlying flow physics and interfacial phenomena at small scales. The different teams are directly or indirectly linked with the topic of soft matter (colloids, drops/bubbles, wetting, interface dynamics, atomization etc.) and bio-fluidics (endothelium mimicking real blood vessels, migrating cancer/tumor cells through capillary microvasculature, paper-and-pencil based microfluidics or microvascular physiology and flow instabilities). Bio/micro fluidics has been a proponent of advances in several new technologies, including electrokinetics, acoustofluidics, optofluidics, magnetofluidics, nanocolloids, and, chemical/biological surface modification, amongst others, together with advanced fabrication methods, molecular/continuum simulation theories, and, imaging and characterization methods. The above-mentioned teams have expertise in all these different methodologies: analytical, numerical (boundary integral method, dissipative particle dynamics, interface-tracking methods: phase-field, Volume of Fluid, Level Set, Lattice Boltzmann Method) and experimental techniques (high-speed imaging, micro-Particle Image Velocimetry, Optical/confocal Microscope, Function Generator, Cell handling, Interferometry, IR Thermography, Femtosecond Laser Micro Fabrication, shadowgraphy etc.). This collaboration will lead to a deep understanding of the topics related to the motions of drops, bubbles, biological cells, contact-line dynamics, non-Newtonian fluids, particle sorting techniques, electrokinetics, cell/particle shape deformation, dielectrophoresis, coalescence and break-up, evaporation, atomization to cite a few. The French and Indian teams will learn and collaborate with each other to understand the fundamentals of the aforementioned topics, in an effort to define extremely focused programs towards solving global research challenges in this rapidly emerging domain.
